To mighty developers: Can ROM cause problems or damage USB connectivity?

Can ROM somehow cause problems with USB recognising of my SGS4 I9505 ?

Shall i try this damaged SGS4 with other ROMs flashing with custom recovery and SD card, or it can only be hardware problem, so no need to try other ROMS ?

My question is simple and i need simple answer (like yes or no). I won't explain how many threads i've checked- simply i'll tell what i've tried.
1. Dozens of cables
2. Few different laptops with different OS
3. A lot USB ports
4. Cleaning phone USB port
5. Replacing with another 2 USB boards from other SGS4
6. Hard phone cache and factory reset

Phone can't be recognized in all modes. Last time it was connecting properly was when i flashed last ROM with Odin. It is STOCK rom. - I9505XXUHOB7_I9505YBTHOB7_DBT-Stock ROM Galaxy s4 and it has received several updates OTA from Samsung.
I have 2 more SGS4 which connects and works fine with all cables. They have never been flashed or rooted.
Shall i try this damaged SGS4 with other ROMs flashing with custom recovery and SD card, or it can only be hardware problem, so no need to try other ROMS ?

THANKS a lot in advance !!!

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Can Certain Toolchain Compilers Cause Instability?

I know with kernels that certain settings work better for different phones/hardware, but I'm wondering if the toolchain that the ROM or kernel is compiled with could lead to instability?

I recently tested Benzo ROM and Uberstock to give the new Uber toolchain a try and see what it was like. I only flashed the ROMs and the recommended Gapps packages for each clean install. Benzo ROM was completely usable but scrolling on my devices would stutter quite a bit.

I also tried Uberstock released by the DespairDev team. Standard Google apps would crash (using slim-gapps-6.0 beta) and the phone would stop responding to my touch.

My question is: Does my phone not like the Uber toolchain or should I be looking for another common thread for this issue? People rave about that toolchain but on builds compiled with it I see a performance decrease compared to stock which is strange.

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